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Flax Hull Lignans Cancer Studies

Flax Hull Lignans bind xenoestrogens

by: Kathy Deane

DNM Kathy Deane

DNM Kathy Deane

Flax History
Flax has been cultivated for over 7,000 years. The Egyptians used its fibre, the Greek physician Dioscorides extolled the flax seeds power for "reducing all inflammation inwardly and utwardly" and Hippocrates encouraged its used for relief of abdominal pains and diarrhea. Charlemagne passed laws requiring the population to consume flax seed “in order to maintain good health”.
Flax Hull Lignans are considered a Superfood today because Flax Hull Lignans biological properties are unique in promoting health & combating diseases. In fact, you would need 100 Tbsp of flax seeds to equal the lignan content of just 1 Tbsp of NSP's Flax Hull Lignans. It’s worth noting that flaxseed oil does not contain appreciable amounts of lignans. Did you know that one teaspoon of concentrated Flax Hull Lignans contains the nutritional equivalent of two gallons of flax seed oil? While flax seed oil has great health benefits there are virtually no lignans contained in the oil.

Flax is higher than soy in isoflavone and while soy can interfere with thyroid function, flax has no such problems. Soya, rye, buckwheat, millet and barley seed yield just 2-6 micrograms of lignans per gram (mcg/g) while Flax seed yields an amazing 800 mcg/g or 400 times more lignans!
Flax is one of the most ancient of useful herbs. Flax was traditionally used for culinary and healing purposes. The essential fatty acids in flax oil are the best-known constituents in the flax seed for providing health benefits. Recent studies have revealed that the substance called “lignan” within the flax seed may surpass flax oil in its health benefits. Lignans are a group of phytonutrients (plant nutrients) which are found in seeds, grains and vegetables. Flax seed is by far nature’s richest source of plant lignans. The lignans are found in the fibre hull of the seed. Flax seed contains a total of 27 different lignans, the first one being SDG. (secoisolariciresinol diglycoside).” NSP Fact Sheet
• SDG lignan is a potent antioxidant and has also been shown to enhance immune system functioning.

• Lignans are considered phytoestrogens. These compounds are able to mimic the hormone estrogen in the body and may reduce the effects of estrogen overload.
• Flax Hull Lignans contains flax fibre, which is very beneficial to the digestive tract. Flax fibre behaves as a gentle laxative by adding bulk to the stool, which in turn promotes regularity.
Since their discovery in 1956, lignans have come under intense scientific scrutiny with numerous studies suggesting they may prevent the development of breast, prostate, colon & other cancers. However no one knew how to obtain flax lignans in high quantity until a farmer in North Dakota by the name of Curtis Rangeloff invented the process.

Curtis Rangeloff says that God answered him in response to prayer and showed him how to obtain the flax lignans. With the help of his friend Dennis Maw, they figured out how to isolate the hulls with the lignans intact; a process which had previously stumped medical scientists. Previously, removing the soft pulp resulted in its destruction, or more correctly, destroying much of its medical usefulness. Their proprietary process extracts the Lignans in such a way that it provides 1000 times the cancer cell destroying capabilities of just plain flax. Both of these farmers credit learning the secret to this process by attending the World Flax Conference held in Fargo, ND for the last 10 years. It was this knowledge, research, and prayers that blessed them with the idea of inventing the world's first chemical-free method of mechanically separating the lignan-rich hulls from the rest of the flax in a manner that prevents rancidity and allows for a stable, effective product for consumer use.

Concentrated Flax hull lignans boast a pure lignan content of up to 65%. Each scoop of the product contains 150-300 mg of SDG per serving. That's 70 times the amount of SDG typically contained in the same amount of traditional ground flax seed.

In addition to their lignan content, flax seed hulls contain high levels of Omega-3s, as well as off-the-charts antioxidants.
Kale has one of the highest ORAC values (this is the measurement of a food's antioxidant content) at 1,770 per 100 grams.
Concentrated Flax Hull Lignans? They come in at a whopping 19,600 per 100 grams. The hulls also contain 4.3g of fiber and 2.8g of protein in each tablespoon.
The true value of the Flax Hull Lignans product is in its promise as a potent cancer killer.
The lignans of the flax help balance hormonal levels in both men and women. It is the SDG lignan that balances estrogen levels in the body. This is the reason why scientists have regarded it seriously by testing to see the influence of flax on cancer, an estrogenic condition. Estrogen causes cells to proliferate. Excess estrogen is not necessarily a good thing, however. There is actually "good" estrogen and "bad" estrogen. For example, we are exposed to too much estrogen in the environment through pesticides and chemical exposure, and through our diet (simple carbohydrates tend to increase insulin production, which in turn, increases the wrong kind of estrogen in our body).

Flax seems to encourage the good estrogen to be created, and at the same time discourage the bad estrogen from developing. Therefore, flax appears to help create a balance of this hormone. During menopause, when the body may be low in estrogen, flax can help the body think it has more estrogen thus helping relieve some of the uncomfortable side effects, such as hot flashes.
Research has shown that people who consume a high intake of lignans in their diet have markedly lower cancer rates. Lignans not only have anti-cancer properties, they have anti-viral, anti-bacterial, and anti-fungal properties. Flax hulls contain potent nutrients that have the potential to enhance immune system functioning and are effective against many different diseases (such as colon cancer, breast cancer, diabetes, lupus, prostate cancer, etc.).

Why Choose NSP's Flax Hull Lignans

87 % of people purchase over the counter health supplements. Did you know that a natural content of just 10% is enough to label a product natural? In health and beauty products it's just 4%.
The scientists at Nature’s Sunshine (NSP) have invested their considerable research and development resources with advanced manufacturing and quality assurance expertise to introduce the finest nutrient dense certified organic food product Flax Hull Lignans. Bulk 150/g 30-day supply.
NSP’s Flax Hull Lignans deliver high value and a unique solution:
• Use a unique mechanical extraction process that leaves all 27 lignans in the final product whereas many other companies use a chemical extraction process that is less efficient and only retains the SDG
• Sourced from organically-grown brown flax and it's certified organic
• Contain 8 – 9% lignans, that's 4-5 times most competitive products
• GEM – Germination Enhancement Method Germination of seeds is all synchronized so root system is 5 times more extensive therefore creating much more nutrient rich food
• 52% fibre of flax hulls lignans
• Economical at up to 30% lower cost than competitive products
Health benefits Of Flax Hull Lignans for men and women:
• As a potent antioxidant, it has been shown to enhance immune system functioning
• Healthy cholesterol maintenance and cardiovascular health
• Protection against muscle damage in athletes and physical labourers
• Reduce the effects of estrogen overload by restoring hormonal balance and promoting normal ovulation
• Overcome symptoms of menopause and a safe alternative to HRT with no risky side effects
• Cancer fighting and prevention properties
• Bone mineral density and protection against calcium loss
• Reduced development of Type II and retarded development of Type I Diabetes
• Long observed and prized for its ability to reduce inflammation, abdominal pain and diarrhea
• Beneficial to the digestive tract by adding bulk which in turns promotes daily regularity

Additional research has shown that Flax Hull Lignans may prevent many types of coronary heart disease, diabetes and promote many other benefits.

Research Tells US

• Flax seeds are by far the richest source of cancer-fighting plant lignans - Beth M. Ley Ph.D
• An early 1980’s study found: Cancer patients have LOWER levels of lignans than tumour-free controls”
• An Australian study (Lancet, 1997) suggested “substantial reduction in breast cancer risk among women with high intake of phytoestrogens, particularly lignans.”
• Denmark-Wahnefried (2001) “men with prostrate issues may experience benefits as a study suggests favourable effect on prostate cancer biology”
• A Swedish study found decreased PSA after just 6 months
• A study at U Saskatchewan shows “73% reduction of plaque build-up in the arteries, and also a reduction of total and LDL cholesterol”
• Studies found “reduced development of Type II diabetes by 80% and Type I diabetes by 73%”
• Another Study shows the positive effects on bone mineral density and to protect against calcium loss
• Reported by Phytotherapy Research in 1995, “pre-treatment with a Lignan-enriched extract was protective against physical exercise-induced muscle damage”
• Stage 4 cancer patients cancer free within two months
• Tumor metastasis reduced by 82 percent.
• A human study in which 31 percent of caner cells were flat out killed in thirty days
• Mice fed flax Hull Lignans ended up with half the tumors of the control group
• Type 2 diabetes have stopped needing shots of insulin
• Men with enlarged prostate sleeping better at night
• In a 90 – day anecdotal test on 100 people with HIV ( 75 percent exhibiting full AIDS symtoms), 97 percent reported postitie health changes, with energy and appetities increasing. After 6 weeks, 28 percent had viral loads drop to non-detectible levels (HIS)

Using NSP Flax Hull Lignans Everyday
Just ½ Tbsp (5/g) daily is all you need though your natural health practitioner may safely suggest more depending on your state of health.
• Sprinkle on salads and cereals
• Add to your rice
• Mix in with your steamed veggies
• Blend into smoothies
A 30-day supply of Flax Hull Lignans amounts bursting with the natural wholesome goodness of a nutrient rich plant, one your body will recognize and efficiently assimilate as food!
It’s an all-natural organic food, it's simple to use, it delivers exceptional health benefits, fits the lifestyle of even the busiest people and is nutritionally economical and a terrific preventative health product.
This informative article appeared in HSI Alert, the newsletter of Health Sciences Institute:
• SDG's effects on cancer is nothing short of incredible. The most exciting study was carried out in Canada on a group of postmenopausal women with newly-diagnosed breast cancer. Each day for a month, the women in the test group ate a flaxseed muffin containing a predetermined concentration of SDG. After only one month, the growth of the cancer cells was reduced by 34.2%. Even better, 31% of cancer cells were completely killed, and the expression of the cancer growth receptor Her2 (c-erB2) decreased by 71%.
• Driving Cancer Cells to Mass Suicide In two studies on breast cancer cells implanted into immune deficient mice, flax lignans again proved deadly to cancer. Both tumor growth and metastasis were significantly reduced.
• In one of the studies, metastasis to the lungs was reduced by 82 percent. The average number of tumors was also considerably lower in the test group than in the control group.
• A study in California demonstrated that SDG reduced risk of endometrial cancer in some women by 32 percent. This reduced risk was most evident among postmenopausal women who consumed high levels of both isoflavones and lignans.
• Other studies have shown similar reduced risk for uterine and ovarian cancers.
• A clinical trial in Canada found that higher dietary lignan intake was linked to considerable reduction in colorectal cancer risk. And, according to studies with human colon cancer cells, lignans stunt the growth of tumor cells and actually drive them to what can only be described as mass suicide.
• Supplementation with SDG reduced tumors significantly in mice with melanoma. The average number of tumors in the control group was 62, while the average number in the groups of mice receiving SDG was around half that. Tumor size was also decreased.
• The American Cancer Society and the FDA acknowledge the cancer-fighting power of flax lignans.
• The Mayo Clinic says flax seed lignans may inhibit the growth of some breast cancers, and the American Cancer Society cites a study in which the growth rate of cancer cells was slowed in men suffering from prostate cancer.
• The FDA have stated that flax seed lignans have anti-tumor activity and are potentially the richest source of phytoestrogens, and that their significant ability to prevent cancer is recognized by the National Cancer Institute.
• Flax lignans have also been shown to suppress the development of atherosclerosis (chronic inflammation of the arteries due to an accumulation of plaque) in a study on rabbits. The development of atherosclerosis in rabbits treated with the lignans was reduced by 34.4 percent.
• The lignans also lowered LDL cholesterol and raised levels of HDL cholesterol.
• There is discussion in the scientific community that flax lignans may help to lower sugar levels in people with diabetes. While there are no specific studies to this effect, people who are living with diabetes have been vocal about the results they've seen taking Concentrated Flax Hull Lignans. One woman noticed that her blood sugar has been regular, and that she's been feeling healthier in general.
• A 26-year-old man who was diagnosed with type 2 diabetes a few years ago has been struggling to manage his illness ever since. Unable to keep his blood sugar down, he watched helplessly as it regularly spiked to 600, despite taking 40 units of insulin with every shot. Two weeks after he began including Concentrated Flax Hull Lignans in his diet, he noticed a change in how he felt. Now, his blood sugar stays under 200, and he hasn't had to give himself a shot in two months.
• A recent study demonstrated that flax lignans could reduce prostate size. Rats given the human equivalent of 50 mg per day of SDG (remember, Concentrated Flax Hull Lignans contains up to 300 mg per serving) had significantly smaller prostates than those without the SDG supplementation.
• The SDG didn’t just stop prostate growth––it actually helped reduce the size of the prostate.
• A candidate for a pacemaker, Hugh reports his doctor has not mentioned the surgery since he started taking the Concentrated Flax Hull Lignans. His doctor was astonished at his progress, stating he’d never seen such a dramatic improvement. At 71, Hugh is now “bouncing along and mowing and putting up hay and working with his horses and cattle.”
• In a trial using mice, flax inhibited the growth and development of prostate cancer. In a study of 25 men who were scheduled for prostatectomy, supplementation with flax brought significant changes in serum cholesterol, total testosterone, and the free androgen index. Researchers concluded that flax lignans may be a very beneficial food for men battling prostate cancer.

This article is for Health Education Always consult with a qualified practitioner before embarking on any program.
Flax Hull lignans on the immune system is well documented.
The AIDS Research Assistance Institute, which sells the Concentrated Flax Hull Lignans, is a nonprofit organization. All of the proceeds from the sale of the product go to bringing it to orphanages and clinics in Africa, where HIV and AIDS run rampant. What they’ve seen there is nothing short of incredible. Children who were drastically underweight are gaining both weight and energy, and aren’t getting the colds and flu infections they once constantly suffered from, according to Emma Fishlock, a nurse working in Swaziland. These children are rising from their deathbeds to return to school.
In a 90-day anecdotal test on 100 people with HIV (75 percent exhibiting full AIDS symptoms), 97 percent reported positive health changes, with energy and appetites increasing. Most amazing is the fact that, after 6 weeks, 28 percent had viral loads drop to non-detectible levels. Their super-charged immune systems were fighting the virus like they never had before.

As an HSI member, you know that flu shots don’t actually do much for preventing the flu, and at their worst are actually harmful. And flu drugs? Forget it! The virus builds resistance almost as soon as the drugs are put on the market. In 2005, 14.5 percent of flu viruses were resistant to major flu drugs. That might not sound like a lot, but compare it to the fact that only 1.9 percent of flu viruses were resistant just one year earlier.

Luckily, it seems flax lignans can do the same thing for influenza that they are doing for the HIV virus in Africa. When a virus enters the cells of the body, it stimulates hormones that activate the gene p53. When this gene is activated, it actually induces virally infected cells to shut down, thereby preventing the virus from spreading. If this is activated shortly after infection, further viral replication is completely stopped. Based upon recent studies, influenza virus infections can be stopped in this way. Flax lignans, through a series of interactions with the inner workings of the body’s cells, can increase the level of p53 in cells. Long story short, flax lignans can actually help to both prevent flu infections and fight those that already exist.
• Canadian study also suggests that SDG may have a therapeutic role In treating lupus. A Dutch human study showed that flax lignans could be the answer for men and women with hair loss and thinning hair. Yet another, this one on rats, showed potential for liver protection.
NOTE: The product mentioned in the above article is the same product Nature’s Sunshine sells except NSP’s is organic.
Flax Hull Lignans Can Help Protect Men From Prostate Cancer!
Both benign hyperplasia (BPH) and cancer of the prostate are manifest in men beyond the age of 50. Approximately 50% of men greater than 50 years of age will suffer from the symptoms associated with BPH, especially from bladder outlet obstruction. With the ever-increasing proportion of the population over 65 years of age worldwide, BPH is becoming an important medical problem as the world moves into the next millennium. Cancer of the prostate is the second most commonly diagnosed cancer after skin cancer in the male population of the United States, and the second most common cause of death from cancer after that of the lung. Overall, around the world the incidence of carcinoma of the prostate is increasing annually by 2-3%.
The lignans enterodial (ED) and enterolactone (EL), which are converted in the intestinal system from flax hull lignans, provide significant biological effects. Enterolactones have demonstrated anti-estrogen and anti-DHT effects that are of particular importance for the aging prostate gland.
"One study of 25 men with prostate cancer found that a low-fat diet along with ground flaxseed reduced serum testosterone, slowed the growth rate of cancer cells, and increased the death rate of cancer cells." -- The American Cancer Society
Flaxs Hull Lignans are incredibly beneficial for anyone suffering with BPH, prostate cancer, high PSA count, or is generally concerned about getting prostate cancer. According to a study conducted by researchers at Duke University Medical Center, lignans in flaxseed prevent genetically damaged cells from completing their cell cycles, which in turn inhibits the promotion and progression of these precancerous cells into malignant ones, explains Wendy Denmark-Wahnefried, Ph.D., a researcher at Duke University.
Reporting in the June, 2008 Journal of Medicinal Foods, a joint study (Tumor Hospital and Institute, Chinese Academy of Medical Sciences and Peking union Medical College, Beijing, People's Republic of China) concluded that flaxseed hull lignans not only improved LUTS (lower Urinary Tract Symptoms) of the 87 test subjects with enlarged prostates (over a 4-month period), but were also as effective as traditional intervention agents (aopha1A-adrenoceptor blockers and 5alpha-reductase inhibitors) at retarding aberrant (possibly cancerous) cell growth.
A recent study demonstrated that flax lignans could reduce prostate size. Rats given the human equivalent of 50 mg per day of SDG (remember, Concentrated Flax Hull Lignans contains up to 300 mg per serving) had significantly smaller prostates than those without the SDG supplementation. The SDG didn't just stop prostate growth – it actually helped reduce the size of the prostate as well. Current treatments for prostate cancer are radical prostatectomy and radiation therapy.
Flax hull lignans work well for both men and women. Flax Hull Lignans are known to be effective against breast and prostate cancer, heart disease, diabetes, kidney disorders, lupus, skin cancer and melanomas and other conditions. It stands to reason that since these lignans are considered a whole food and enhance the immune system, they would be beneficial across the board. This article is primarily focused on prostate cancer and women's health.
Flax Hull Lignans Can Remove Your Fear of Dying From Breast Cancer
"Phytoestrogens are naturally occurring compounds that lower circulating estrogens in your body. Flaxseed is particularly high in one phytoestrogen, lignan, which appears to decrease estrogen production and which may inhibit the growth of some breast cancers." -- The Mayo Clinic
An imbalance of estrogen in a woman's body is the primary cause of breast cancer. This is usually caused by having too much chemical estrogen from taking birth-control pills, or a lack of estrogen after going through menopause. Since lignans are phytoestrogens (plant estrogens), they are effective in treating a variety of hormone related issues caused by estrogen imbalance. In short term studies women who ate between 1 and 2/12 rounded tablespoons of flaxseed a day had improved estrogen metabolism. If there is little estrogen in the body (after menopause, for example), lignans may act like weak estrogen; but when natural estrogen is abundant in the body, lignans may instead reduce estrogen's effects by displacing it from the cells.
Populations who eat a diet rich in lignans have lower breast cancer. In animal models of breast cancer scientists have discovered that purified SDG lignan reduced tumor size and number of breast tumors. A variety of human studies indicate that flax lignans may have protective benefits against breast cancer. Women consuming lignan-rich flaxseed products generally report a reduction in breast tenderness, bloating, hot flashes, sweating, vaginal dryness, and other symptoms related to PMS and menopause. This is due to the lignan's estrogenic activity.
Hormone Replacement Therapy (HRT) has been shown to cause breast cancer. Millions of women are looking for natural alternatives to modulate and balance their body's estrogen and flax lignans are what you need. In one study they found that flaxseed was as effective as hormone replacement therapy in reducing mild menopausal symptoms in menopausal women.
For years, people have been attempting to control menstrual cycles. Controlling menstrual cycles has several health benefits including decreasing the risk of breast cancer. Lignans in flaxseed have been shown to regulate women's menstrual cycles. In one study, women consuming lignans in flaxseed did not miss a single cycle, compared to the control group that missed several cycles. In another study women supplemented their diet with a dose of 10 g/day of flax. It resulted in elevated progesterone / estradiol ratios in the luteal phase. This was due to a decreased estradiol concentration. The concentration of lignans measured in the urine showed the level of lignans absorbed. Thus flax lignan clearly has a significant impact in controlling women's menstrual cycle.
Many ladies have stated that tumors in their breast are shrinking within 1 to 3 weeks of being on the flax hull lignans while also claiming that their Hot flashes are leaving altogether too, and only occurring once in a while, in some cases.
In a study with rats, the effect of flax and its lignan SDG was compared with tamoxifen, an anti-estrogen drug, by monitoring rat estrous cycling. After four weeks 66% of the rats taking flax SDG had more regular cycling produced by a cessation or lengthening (by 18-39%) of estrous cycles. In the rats given tamoxifen, 83% of the animals had irregular cycles or were in persistent diestrous.
The control which lignan has over the menstrual cycle has an influence on cancer growth. This is because the less time a women spends in the luteal phase, the lower the risk of breast cancer.
A study of twenty-eight post-menopausal women was conducted in which they consumed lignan-rich flaxseed. The supplementation significantly increased urinary excretion of the estrogen metabolites 2-hydroxyestrogen and 16 alpha-hydroxyestrone. These results suggest that lignan from flaxseed may have chemo-protective effects in post-menopausal women.
Flax Hull Lignans & Lung Cancer
Lignans have attracted considerable scientific attention in recent years thanks to their potential ability to act as highly effective chemo-preventive agents in lung cancer, according to Christofidou-Solomidou, Ph.D., a professor of medicine at the University of Pennsylvania Medical Center. Christofidou-Solomidou and colleagues have examined the antioxidant effects of lignans and their protective effects against DNA oxidation in murine models of lung carcinogenesis. The analysis of these experiments indicate that lignans can substantially suppress the proliferation of chemical-carcinogenesis-induced lung cancer cells.
More Stories & Studies Proving Flax Hull Lignans Benefits
To date, more than 100 studies have been published, examining the bioavailability and metabolism of flax lignans, as well as their various health benefits for men and women.
There is considerable evidence from epidemiological studies correlating high concentrations of lignans in the body fluids with a low incidence of hormone-dependent tumors, in particular breast cancer.
Kulling SE Jacobs E Pfeiffer E Metzler M
Studies on the genotoxicity of the mammalian lignans enterolactone and enterodiol and their metabolic precursors at various endpoints in vitro. In: Mutat Res (1998 Aug 7) 416(1 2):115 24
Excretion of both equol and enterolactone was associated with a substantial reduction in breast-cancer risk, with significant trends.
Ingram D Sanders K Kolybaba M Lopez D
Case control study of phyto oestrogens and breast cancer
In: Lancet (1997 Oct 4) 350(9083):990 4
There is a substantial reduction in breast cancer risk among women with a high intake (as measured by excretion) of phyto-oestrogens - particularly the isoflavonic phyto-oestrogens equol and the lignan enterolactone. These findings could be important in the prevention of breast cancer.
Ingram D Sanders K Kolybaba M Lopez D
Case control study of phyto oestrogens and breast cancer
In: Lancet (1997 Oct 4) 350(9083):990 4
The lower excretion of enterolactone by breast cancer patients in our study accords with the findings of a previous small study (seven cases) in which enterolactone excretion was significantly lower in post-menopausal breast cancer patients than in omnivorous and vegetarian controls.
Ingram D Sanders K Kolybaba M Lopez D
Case control study of phyto oestrogens and breast cancer
In: Lancet (1997 Oct 4) 350(9083):990 4
Mammalian lignans inhibit the growth of human breast cancer cells and partially inhibit angiogenesis.
Rickard SE Orcheson LJ Seidl MM Luyengi L Fong HH Thompson LU
Dose dependent production of mammalian lignans in rats and in vitro from the purified precursor secoisolariciresinol diglycoside in flaxseed.
In: J Nutr (1996 Aug) 126(8):2012 9
Epidemiological studies indicated that plasma levels and urinary excretion of the lignan and isoflavonoid phytoestrogens correlated negatively with rates of breast and prostate cancer.
Ren S Lien EJ
Natural products and their derivatives as cancer chemopreventive agents.
In: Prog Drug Res (1997) 48:147 71
Lignans have been extensively investigated for their potential anticancer activity, and several have been used as chemotherapeutic agents.
Axelson M Sjovall J Gustafsson BE Setchell KD
Origin of lignans in mammals and identification of a precursor from plants.
The lignan enterolactone showed a three-fold reduction (reduction in risk for breast cancer) in risk for the highest compared with the lowest quartile of excretion...
Ingram D Sanders K Kolybaba M Lopez D
Case control study of phyto oestrogens and breast cancer In: Lancet (1997 Oct 4) 350(9083):990 4
Many Lignans have antitumor, antimitotic, antioxidant, weak estrogenic and antiestrogenic activities and some have been shown to prevent the growth of many tumors studied in the chemotherapy program of the U.S. National Cancer Institute.
Mammalian Lignan Production From Various Foods Nutrition and Cancer; Lawrence Erlbaum Associates, Inc. 1991
Flax is a potent source of lignans.... studies suggested that they may interfere with the development of breast, prostate, colon, and other tumors in humans.
Journal of the National Cancer Institute. Vol. 86 No.23. December 7, 1994 pg. 1748
They (lignans) have now been shown to influence not only sex-hormone metabolism and biological activity but also intracellular enzymes, protein synthesis, growth factor action, malignant cell proliferation, differentiation and angiogenesis, making them strong candidates as natural cancer chemo-preventative compounds.
Ren S Lien EJ
Natural products and their derivatives as cancer chemopreventive agents.
Feeding of SD (the major mammalian lignan precursor in flaxseed) at 1.5 mg/day resulted in a significant reduction in tumor burden and the number of tumors per number of rats in the group.
Thompson LU Seidl MM Rickard SE Orcheson LJ Fong HH
Antitumorigenic effect of a mammalian lignan precursor from flaxseed.
In: Nutr Cancer (1996) 26(2):159 65
In conclusion, flaxseed oil and flaxseed (in a dose dependant manner) reduced the growth of established tumors at a late stage of carcinogenesis whereas the mammalian lignans precursor S.D. exerted the greatest inhibitory effect on the development of new tumors. In contrast to new tumors, the size of established tumors was inversely related to the level of urinary mammalian lignans indicating that the lignans produced by S.D. played a role in the reduction of established tumor growth.
Thompson LU Rickard SE Orcheson LJ Seidl MM
Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis.
In: Carcinogenesis (1996 Jun) 17(6):1373 6
Sources of Information For This Story:
Flax: The genus Linum; Edited by Alister D. Muir and Neil D. Westcott, Taylor & Francis, 2003.. Flaxseed Lignan: The Power of SDG in Promoting Health. Weisman, Charles A., Junker, Daniel, Weisman Publications, May, 2003.. Flax Lignan Information Bureau Duke Cancer Institute: Flaxseed Stunts The Growth of Prostate Tumors
The Health Sciences Institute
SOURCE: Crusador, "Anti-Cancer Breakthrough Discovered In The Hull of Flaxseeds," (2014).
SOURCE: Michael Greger M.D., "Flax and Breast Cancer Prevention," http://nutritionf


Articles by Kathy Deane

Kathy Deane Health Educator & Nutritional Consultant. for 30 years holds her DNM Doctorate in Natural Medicine, RHP Registered Herbal Practitioner & RNP Registered Naturotherapy Practitioner and is a FITness Coach. Kathy specializes in helping people meet HEALTHY LIFESTYLE GOALS using DIET, EXERCISE, HERBAL & VITAMIN SUPPLEMENTATION. Education is my love states Deane. CORRESPONDENCE PROGRAMS are AVAILABLE IN 36 COUNTRIES. FREE LIFESTYLE ANALYSIS @

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